Impact of submandibular gland excision on salivary gland function in head and neck cancer patients

摘要: Head and neck cancer surgery is often associated with dissection usually includes the submandibular glands. Literature data related to remaining salivary gland function after scarce controversial. A reduction in output increase complaints of xerostomia have been suggested. However, a compensatory mechanism has also reported. The aim this prospective study was evaluate effect (with excision) on measured by flow rate scintigraphy. total 80 patients head tumors were evaluated. group composed 37 patients, who underwent resection, non-surgery 43 evaluated prior radiation and/or chemotherapy treatment. Whole unstimulated stimulated saliva collection scintigraphy performed all patients. Twenty-one percent reported xerostomia, whereas 7% group. mean 0.60 0.94 m/min for groups, respectively (p=0.008). Nevertheless, no statistical difference observed between groups (p=0.26). In addition, uptake excretion rates parotid glands showed difference. present support contention that resection causes decrease volume. residual similar Consequently, seems not be possibility.