Is Liquid-Based Cytology the Magic Bullet for Performing Molecular Techniques?

作者: Behnoush Abedi-Ardekani , Philippe Vielh

DOI: 10.1159/000366260

关键词:

摘要: Objective: The role of pathology has evolved from the first microscopic definitions diseases by Virchow to new concept molecular cytopathology. management is now a multidisciplinary approach with translation morphological, imagery and findings therapeutic protocols. Obtaining most reliable diagnostic material essential part medical patients. Study Design: Here, we try gain concise insight into available data regarding cytology in application techniques, focusing on cancer Results: cytological feasible different methods, some cases it only possible lesion which not easily accessible for tissue sampling. methods obtaining have recent years parallel rapid advances high-throughput opening windows diagnosis diseases. Conclusions: Different kinds are techniques. Cytological obtained liquid base advantages such as better preservation cytomorphological features use remaining nucleic acid extraction even after long storage methods.

参考文章(72)
Esther Diana Rossi, Maurizio Martini, Sara Capodimonti, Celestino Pio Lombardi, Alfredo Pontecorvi, Valerio Gaetano Vellone, Gian Franco Zannoni, Luigi Maria Larocca, Guido Fadda, BRAF (V600E) mutation analysis on liquid-based cytology-processed aspiration biopsies predicts bilaterality and lymph node involvement in papillary thyroid microcarcinoma. Cancer Cytopathology. ,vol. 121, pp. 291- 297 ,(2013) , 10.1002/CNCY.21258
, A genomics-based classification of human lung tumors Science Translational Medicine. ,vol. 5, pp. 1- 28 ,(2013) , 10.1126/SCITRANSLMED.3006802
Tae Hyuk Kim, Young Joo Park, Jung Ah Lim, Hwa Young Ahn, Eun Kyung Lee, You Jin Lee, Kyung Won Kim, Seo Kyung Hahn, Yeo Kyu Youn, Kwang Hyun Kim, Bo Youn Cho, Do Joon Park, The association of the BRAFV600E mutation with prognostic factors and poor clinical outcome in papillary thyroid cancer Cancer. ,vol. 118, pp. 1764- 1773 ,(2012) , 10.1002/CNCR.26500
Gilda da Cunha Santos, Mauro Ajaj Saieg, William Geddie, Natasha Leighl, EGFR gene status in cytological samples of nonsmall cell lung carcinoma: controversies and opportunities. Cancer Cytopathology. ,vol. 119, pp. 80- 91 ,(2011) , 10.1002/CNCY.20150
Bryan L. Betz, Catherine A. Dixon, Helmut C. Weigelin, Stewart M. Knoepp, Michael H. Roh, The use of stained cytologic direct smears forALKgene rearrangement analysis of lung adenocarcinoma Cancer Cytopathology. ,vol. 121, pp. 489- 499 ,(2013) , 10.1002/CNCY.21286
Sung Hak Lee, Chan Kwon Jung, Ja Seong Bae, So Lyung Jung, Yeong Jin Choi, Chang Suk Kang, Liquid-based cytology improves preoperative diagnostic accuracy of the tall cell variant of papillary thyroid carcinoma. Diagnostic Cytopathology. ,vol. 42, pp. 11- 17 ,(2014) , 10.1002/DC.23007
T. Hansen, H. Pedersen, V. Brauner, J. Hariri, Control specimens for immunocytochemistry in liquid-based cytology. Cytopathology. ,vol. 22, pp. 243- 246 ,(2011) , 10.1111/J.1365-2303.2010.00755.X
N. K. B. Pang, M. E. Nga, S. Y. Chin, T. M. Ismail, G. L. Lim, R. Soong, M. Salto-Tellez, KRAS and BRAF mutation analysis can be reliably performed on aspirated cytological specimens of metastatic colorectal carcinoma. Cytopathology. ,vol. 22, pp. 358- 364 ,(2011) , 10.1111/J.1365-2303.2010.00812.X
Enrico Pegolo, Piernicola Machin, Franca Riosa, Anna Bassini, Laura Deroma, Carla Di Loreto, Hormone receptor and human epidermal growth factor receptor 2 status evaluation on ThinPrep specimens from breast carcinoma: correlation with histologic sections determination. Cancer Cytopathology. ,vol. 120, pp. 196- 205 ,(2012) , 10.1002/CNCY.20206