Propofol infusion versus intermittent meperidine and midazolam injection for conscious sedation in ERCP.

摘要: BACKGROUND AND AIM: ERCP generally requires longer time than standard endoscopy. Only few studies have shown benefit of intermittent propofol over conventional sedation. This study was conducted to compare satisfaction, recovery score, and recovery/safety profiles for sedation between continuous infusion PATIENTS METHODS: One hundred thirty-four patients with ASA I-III underwent were randomly assigned into two groups (n=67 each). Patients or meperidine/midazolam Supplemental oxygen offered only when saturation lower 90 %. Oxygen saturation, blood pressure, heart rate, times satisfaction score after procedure recorded analyzed. RESULTS: Average amount meperidine, midazolam per each patient 61.54 (+/- 27.29), 7.80 3.73), 299.90 146.15) mg, respectively. Time regain full consciousness in the arm significantly shorter (17.24 +/- 5.99 versus 34.25 16.06 min, p<0.001). The rates desaturation, bradycardia hypotension both arms low comparable. Propofol provided higher level scores at 15, 30, 45 60 min (p < 0.001). CONCLUSION: Continuous by direction gastroenterologist yields no difference completion rate adverse compared technique but it provides a better profile. maintainance appropriate well trained personnel is key achieve this success.