Disruption of the mevalonate pathway induces dNTP depletion and DNA damage.
作者： Covadonga Martín Sánchez , José Manuel Pérez Martín , Jong-Sik Jin , Alberto Davalos , Wei Zhang
DOI: 10.1016/J.BBALIP.2015.06.001
关键词:
摘要: … of recombinant stretches of single-stranded DNA (ssDNA) … biosynthesis and the supply of exogenous deoxyribonucleosides … for a sufficient deoxyribonucleotide supply to sustain DNA …
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Javier Martı́nez-Botas, Antonio J Ferruelo, Yajaira Suárez, Carlos Fernández, Diego Gómez-Coronado, Miguel A Lasunción, Dose-dependent effects of lovastatin on cell cycle progression. Distinct requirement of cholesterol and non-sterol mevalonate derivatives. Biochimica et Biophysica Acta. ,vol. 1532, pp. 185- 194 ,(2001) , 10.1016/S1388-1981(01)00125-1
Yajaira Suárez, Carlos Fernández, Beatriz Ledo, Antonio J. Ferruelo, Miguel Martín, Miguel A. Vega, Diego Gómez-Coronado, Miguel A. Lasunción, Differential effects of ergosterol and cholesterol on Cdk1 activation and SRE-driven transcription. FEBS Journal. ,vol. 269, pp. 1761- 1771 ,(2002) , 10.1046/J.1432-1327.2002.02822.X
B Nicander, P Reichard, Relations between synthesis of deoxyribonucleotides and DNA replication in 3T6 fibroblasts. Journal of Biological Chemistry. ,vol. 260, pp. 5376- 5381 ,(1985) , 10.1016/S0021-9258(18)89032-9
H W Chen, Role of cholesterol metabolism in cell growth. Federation proceedings. ,vol. 43, pp. 126- ,(1984)
J A Cuthbert, P E Lipsky, Inhibition by 6-fluoromevalonate demonstrates that mevalonate or one of the mevalonate phosphates is necessary for lymphocyte proliferation. Journal of Biological Chemistry. ,vol. 265, pp. 18568- 18575 ,(1990) , 10.1016/S0021-9258(17)44789-2
J.A. Cuthbert, P.E. Lipsky, Negative regulation of cell proliferation by mevalonate or one of the mevalonate phosphates. Journal of Biological Chemistry. ,vol. 266, pp. 17966- 17971 ,(1991) , 10.1016/S0021-9258(18)55223-6
Hiroshi Tanaka, Hirofumi Arakawa, Tatsuya Yamaguchi, Kenji Shiraishi, Seisuke Fukuda, Kuniko Matsui, Yoshiki Takei, Yusuke Nakamura, A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage Nature. ,vol. 404, pp. 42- 49 ,(2000) , 10.1038/35003506
Gurmit Singh, Susan Sweet, Accumulation of human promyelocytic leukemic (HL-60) cells at two energetic cell cycle checkpoints. Cancer Research. ,vol. 55, pp. 5164- 5167 ,(1995)
M S Brown, J L Goldstein, Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth Journal of Lipid Research. ,vol. 21, pp. 505- 517 ,(1980) , 10.1016/S0022-2275(20)42221-7
Charles J. Sherr, The Pezcoller lecture: cancer cell cycles revisited. Cancer Research. ,vol. 60, pp. 3689- 3695 ,(2000)