Immobilization of Metal–Organic Frameworks on Supports for Sample Preparation and Chromatographic Separation

摘要: Metal–organic frameworks (MOFs) are porous crystalline materials with large surface areas, uniform pore size, and tunable selectivity. In the last few years, number of analytical applications MOFs has been growing constantly. However, direct use as-synthesized in packed column format is rather limited for separations because small size non-spherical shape MOF crystals. this review, we outline critically discuss advantages limitations different methods described to immobilize into functional supports separations, including beads, monoliths, fibers. These based on embedding crystals supports, situ growth, controlled layer-by-layer or conversion immobilized metal oxide precursors. Representative examples sample preparation chromatographic separation overviewed. We also overview recent progress as precursors obtain other such layered double hydroxides carbons.