Zur Prophylaxe von Periartikulären Verknöcherungen - mit Ergebnissen einer randomisierten, doppelblinden Studie zum Vergleich von Acemetacin versus Indometacin

摘要: We examined the effect of NSAR in prophylaxis heterotopic ossifications after hip arthroplasty. During a randomized doubleblind study 59 patients took Indometacin and 60 Acemetacin for three weeks operation. All them got thrombosis with Heparin short term antibiotic prophylaxis. The range was checked months operation according to Arcq. proportion no clinical symptoms (grade 0 or 1) 92.3% indometacin group 98.2% acemetacin group. Because side effects (mainly gastrointestinal) 7 (11.9%) 5 (8.3%) stopped study. In previous we had by on ossifications. These results could now be taken comparison. According these raised low grade higher grades (2 degrees 3 Arcq) were only seen less than 5%. That is why recommend (Acemetacin Indometacin) generally arthroplasty as