INHIBITION OF DNA DAMAGE REPAIR BY ARTIFICIAL ACTIVATION OF PARP WITH OLIGONUCLEOTIDE MOLECULES

作者: Sun Jian-Sheng , Dutreix Marie

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摘要: The present application relates to a new class of PARP inhibitors and their uses as drug, especially for use in cancer therapy. These include double stranded portion with nick or gap on one strand the tethered 5' 3' ends two extremities portion.

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