Heat susceptibility of interleukin-10 and other cytokines in donor human milk.
作者： Peter B. Untalan , Susan E. Keeney , Kimberly H. Palkowetz , Audelio Rivera , Armond S. Goldman
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摘要: Abstract Objective: Holder pasteurization renders donor human milk safe for consumption. Because reduces the risk of necrotizing enterocolitis in preterm infants, we tested whether affects certain factors that protect intestines: epidermal growth factor (EGF), transforming (TGF)-β1, erythropoietin (EPO), and interleukin (IL)-10. Donor from a bank was examined. Methods: The aqueous phase 17 samples term (mean duration lactation, 8 ± 3.5 months) examined before after pasteurization. In case IL-10, lesser degrees were also evaluated. agents quantified using enzyme immunoassays. function IL-10 tested. Results: Concentrations EGF markedly lower than previously reported values earlier phases lactation. significantly reduced concentrations EPO whereas degree...
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