Hemodynamic Response to Oxygen Therapy in Chronic Obstructive Pulmonary Disease

作者: RICHARD M TIMMS , FAREED U KHAJA , GEORGE W WILLIAMS

DOI: 10.7326/0003-4819-102-1-29

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摘要: At six centers, 203 patients with stabilized hypoxemic chronic obstructive pulmonary disease were evaluated hemodynamically during a continuous or 12-hour oxygen therapy program. Neither program resulted in correction near-correction of the baseline hemodynamic abnormalities. The group did show improvement vascular resistance, arterial pressure, and stroke volume index. resistance was associated improved cardiac function, as evidenced by an increase exercise nocturnal showed stable variables. For both groups, changes mean artery pressure first 6 months subsequent survival after adjustment for association pressure. Continuous can improve abnormalities hypoxic disease. response to this treatment is predictive survival.

参考文章(29)
David R. Cox, Regression Models and Life-Tables Springer Series in Statistics. ,vol. 34, pp. 527- 541 ,(1992) , 10.1007/978-1-4612-4380-9_37
Giles F. Filley, Henry J. Beckwitt, John T. Reeves, Roger S. Mitchell, Chronic obstructive bronchopulmonary disease. II. Oxygen transport in two clinical types. The American Journal of Medicine. ,vol. 44, pp. 26- 38 ,(1968) , 10.1016/0002-9343(68)90234-9
Fareeduddin Khaja, John O. Parker, Right and left ventricular performance in chronic obstructive lung disease. American Heart Journal. ,vol. 82, pp. 319- 327 ,(1971) , 10.1016/0002-8703(71)90298-5
James H. Ellis, D. Kirch, Peter P. Steele, Right ventricular ejection fraction in severe chronic airway obstruction. Chest. ,vol. 71, pp. 281- 282 ,(1977) , 10.1378/CHEST.71.2_SUPPLEMENT.281
E. L. Kaplan, Paul Meier, Nonparametric Estimation from Incomplete Observations Springer Series in Statistics. ,vol. 53, pp. 319- 337 ,(1992) , 10.1007/978-1-4612-4380-9_25
A P Fishman, Hypoxia on the pulmonary circulation. How and where it acts. Circulation Research. ,vol. 38, pp. 221- 231 ,(1976) , 10.1161/01.RES.38.4.221
Donald A. Weiner, Normal Hemodynamic, Ventilatory, and Metabolic Response to Exercise Archives of Internal Medicine. ,vol. 143, pp. 2173- 2175 ,(1983) , 10.1001/ARCHINTE.1983.00350110163032
ABRAHAM S. ABRAHAM, RICHARD B. COLE, JOHN M. BISHOP, Reversal of Pulmonary Hypertension by Prolonged Oxygen Administration to Patients with Chronic Bronchitis Circulation Research. ,vol. 23, pp. 147- 157 ,(1968) , 10.1161/01.RES.23.1.147
A. Lockhart, F. Nader, M. Tzareva, F. Schrijen, Comparative effects of exercise and isocapnic voluntary hyperventilation on pulmonary haemodynamics in chronic bronchitis and emphysema. European Journal of Clinical Investigation. ,vol. 1, pp. 69- 76 ,(1970) , 10.1111/J.1365-2362.1970.TB00599.X