Morbidity and mortality of craniotomy for excision of supratentorial gliomas

摘要: Extensive surgical resection of supratentorial gliomas increases survival. However, some reports suggest that the perioperative morbidity and mortality outweigh potential benefit procedure. We examined prospectively in 104 consecutive patients who underwent surgery for glioma, as well other factors might affect short-term outcome. To determine if our experience was unusual, we compared these results with those obtained from another academic neurosurgical center by a review records 109 also treated surgically glioma. Mortality 3.3% medical plus neurologic 31.7%. Functionally significant worsening occurred 42 (19.7%) patients. Complications were more frequent moderate or severe preoperative disabilities than mild no disability. Patients complete had fewer acute complications, greater risk being neurologically impaired at 1 week, biopsy less extensive procedures. Morbidity correlated location: deep-midline lesions higher overall rate complications ( p = 0.032) 0.019) bilateral hemorrhage 0.017) hydrocephalus 0.010). Older (>55 years) receiving high daily dose dexamethasone (≥24 mg) significantly mortality. Reoperation recurrent tumor carried mortality, deterioration, infection first operation. Whenever possible, maximal should be offered to gliomas, because it does not carry biopsy, long-term outcome is superior.