Physiochemical characterization and anti-carbapenemase activity of chitosan nanoparticles loaded Aegle marmelos essential oil against K. pneumoniae through DNA fragmentation assay
作者： Shine Kadaikunnan , Jamal M. Khaled , Natesan Manoharan , Wen-Jun Li , Wen-Jun Li
DOI: 10.1016/J.SURFIN.2021.100932
关键词:
摘要: Abstract The Aegle marmelos essential oils (AMEOs) were loaded on surface of the chitosan nanoparticles (CHs NPs), and it performed against carbapenemase producing K. pneumoniae. physiochemical characterizations CHs, CHs NPs AMEOs-CHs confirmed by FTIR powder XRD. morphological observation, size, shape SEM TEM results that AMEOs was successfully coated onto surface. Further, excellent minimum inhibitory activity CR pneumoniae observed at 40 μg/mL. increased death cells, damages, modification confocal laser scanning electron microscope, microscope transmission respectively. In addition, invitro anti-carbapenemase activity, changed color intensity treated result has carbapenenemase enzyme degradation ability. Importantly, fragmented DNA suppressed VIM 1 IMP genes expression clearly indicated very anti-bacterial material. Finally, molecular docking more supported to evidences, proved as valuable biomaterials owing their ability fight multi drug resistance bacteria.
sci-hub.st 参考文章(52)
Govindan Rajivgandhi, Thillaichidambaram Muneeswaran, Muthuchamy Maruthupandy, Chockalingam Muthiah Ramakritinan, Kandasamy Saravanan, Vilwanathan Ravikumar, Natesan Manoharan, None, Antibacterial and anticancer potential of marine endophytic actinomycetes Streptomyces coeruleorubidus GRG 4 (KY457708) compound against colistin resistant uropathogens and A549 lung cancer cells. Microbial Pathogenesis. ,vol. 125, pp. 325- 335 ,(2018) , 10.1016/J.MICPATH.2018.09.025
Nabaweya A Ibrahim, Magdy MD Mohammed, Hanan F Aly, Sanaa Ahmed Ali, Doaa-Abd Al-Hady, None, Efficiency of the leaves and fruits of Aegle marmelos methanol extract (L.) Correa and their relative hepatotoxicity induced by CCL4 and identification of their active constituents by using LC/MS/MS. Toxicology reports. ,vol. 5, pp. 1161- 1168 ,(2018) , 10.1016/J.TOXREP.2018.09.005
Rafael Gomes Von Borowski, Karine Rigon Zimmer, Bianca Franco Leonardi, Danielle Silva Trentin, Rodrigo Campos Silva, Muriel Primon de Barros, Alexandre Jose Macedo, Simone Cristina Baggio Gnoatto, Grace Gosmann, Aline Rigon Zimmer, None, Red pepper Capsicum baccatum: source of antiadhesive and antibiofilm compounds against nosocomial bacteria Industrial Crops and Products. ,vol. 127, pp. 148- 157 ,(2019) , 10.1016/J.INDCROP.2018.10.011
Zhaojie Wang, Hu Bai, Chunbo Lu, Chunyan Hou, Yuanhao Qiu, Peng Zhang, Jinyou Duan, Haibo Mu, Light controllable chitosan micelles with ROS generation and essential oil release for the treatment of bacterial biofilm. Carbohydrate Polymers. ,vol. 205, pp. 533- 539 ,(2019) , 10.1016/J.CARBPOL.2018.10.095
Lin Lin, Xuefang Mao, Yanhui Sun, Govindan Rajivgandhi, Haiying Cui, Antibacterial properties of nanofibers containing chrysanthemum essential oil and their application as beef packaging International Journal of Food Microbiology. ,vol. 292, pp. 21- 30 ,(2019) , 10.1016/J.IJFOODMICRO.2018.12.007
Govindan Rajivgandhi, Muthuchamy Maruthupandy, Thillaichidambaram Muneeswaran, Govindan Ramachandran, Natesan Manoharan, Franck Quero, Muthusamy Anand, Ji-Ming Song, None, Biologically synthesized copper oxide nanoparticles enhanced intracellular damage in ciprofloxacin resistant ESBL producing bacteria. Microbial Pathogenesis. ,vol. 127, pp. 267- 276 ,(2019) , 10.1016/J.MICPATH.2018.12.017
Debasish Kumar Dey, Imran Khan, Sun Chul Kang, Anti-bacterial susceptibility profiling of Weissella confusa DD_A7 against the multidrug-resistant ESBL-positive E. coli. Microbial Pathogenesis. ,vol. 128, pp. 119- 130 ,(2019) , 10.1016/J.MICPATH.2018.12.048
Amro Shetta, James Kegere, Wael Mamdouh, Comparative study of encapsulated peppermint and green tea essential oils in chitosan nanoparticles: Encapsulation, thermal stability, in-vitro release, antioxidant and antibacterial activities. International Journal of Biological Macromolecules. ,vol. 126, pp. 731- 742 ,(2019) , 10.1016/J.IJBIOMAC.2018.12.161
Shikha Raheja, Amit Girdhar, Anjoo Kamboj, Viney Lather, Deepti Pandita, Aegle marmelos leaf extract ameliorates the cognitive impairment and oxidative stress induced by intracerebroventricular streptozotocin in male rats Life Sciences. ,vol. 221, pp. 196- 203 ,(2019) , 10.1016/J.LFS.2019.02.032
Lubna Azmi, Ila Shukla, Arti Goutam, Allauddin, Ch.V. Rao, Talha Jawaid, Mehnaz Kamal, Amani S. Awaad, Saleh I. Alqasoumi, Osama A. AlKhamees, In vitro wound healing activity of 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde (HDNC) and other isolates of Aegle marmelos L.: Enhances keratinocytes motility via Wnt/β-catenin and RAS-ERK pathways Journal of The Saudi Pharmaceutical Society. ,vol. 27, pp. 532- 539 ,(2019) , 10.1016/J.JSPS.2019.01.017