CHARACTERISTICS OF METHICILLIN-RESISTANT STAPHYLOCOCCI

作者: R. Sutherland , G. N. Rolinson

DOI: 10.1128/JB.87.4.887-899.1964

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摘要: Sutherland, R. (Beecham Research Laboratories Ltd., Betchworth, Surrey, England), and G. N. Rolinson. Characteristics of methicillin-resistant staphylococci. J. Bacteriol. 87:887–899. 1964.—Cultures naturally occurring staphylococci obtained from a number hospitals were examined for the nature degree resistance to methicillin other antibiotics. All cultures tested similar in that they consisted mixed populations which majority cells normal sensitivity with minority showing resistance. The resistant members also differed rest population grew more slowly even absence methicillin. Pure readily but, on repeated transfer methicillin, was lost reverted original strains. When methicillin-sensitive repeatedly subcultured presence only antibiotic; this respect, selected vitro resembled comprised uniform or insensitivity these not due increased ability inactivate drug but intrinsic

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