Determination of clusters and factors associated with dengue dispersion during the first epidemic related to Dengue virus serotype 4 in Vitória, Brazil

摘要: Dengue occurrence is partially influenced by the immune status of population. Consequently, introduction a new virus serotype can trigger explosive epidemics in susceptible populations. The determination clusters this scenario help to identify hotspots and understand disease dispersion regardless influence population herd immunity. present study evaluated pattern factors associated with dengue during first epidemic related 4 Vitoria, Espirito Santo state, Brazil. Data on 18,861 cases reported Vitoria from September 2012 June 2013 were included study. analysis spatial variation temporal trend was performed detect that compared their respective relative risk, house index, density, income an ecological Overall, 11 detected. time increase incidence overall 636%. five showed lower than presented higher beginning and, six increase, they risk for inhabitants acquire infection (P-value = 0.02) <0.01). House index density did not differ between clusters. Early acquiring favored low-income areas. Preventive actions improvement infrastructure areas should be prioritized order diminish magnitude after serotype.