Risk factors for the incidence of dengue virus infection in preschool children.

作者: Maria G. Teixeira , Vanessa Morato , Florisneide R. Barreto , Carlos M. C. Mendes , Maurício L. Barreto

DOI: 10.1111/J.1365-3156.2012.03086.X

关键词:

摘要: Objective  To estimate the seroincidence of dengue in children living Salvador, Bahia, Brazil and to evaluate factors associated. Methods  A prospective serological survey was carried out a sample 0–3 years age. multilevel logistic model used identify determinants seroincidence. Results  The seroprevalence 26.6% 625 evaluated. second detected an incidence 33.2%. Multilevel regression showed statistically significant association between age premises index. Conclusion  In virus is active circulation during early childhood; consequently, have heterotypic antibodies run high risk developing haemorrhagic fever, because sequence intensity three serotypes currently circulating this city are very similar those that were Rio de Janeiro, Brazil, 2008. Therefore, authors strongly recommend health authorities cities with epidemiological scenario be aware implement improvements care, particularly targeting paediatric groups. addition, information should provided population actions implemented combat vector. Objectif:  Estimer la sero-incidence l’infection chez les enfants vivant Salvador au Bresil et evaluer facteurs associes. Methodes:  Des surveillances serologiques prospectives ont ete realisees sur un echantillon des 0 3 ans. Un modele logistique plusieurs niveaux utilise afin d’identifier sero-incidence. Resultats:  La etait 26,6% evalues. Une deuxieme enquete detecte une 33,2%. L’analyse montre statistiquement significative entre l’âge l’indice premisses. Conclusion:  le est en pendant petite enfance, par consequent, anticorps heterotypiques courent risque eleve developper fievre hemorragique dengue, puisque l’intensite trois du circulant actuellement dans cette ville sont tres semblables ceux qui etaient Janeiro Bresil, Par auteurs recommandent vivement aux autorites sante villes avec epidemiologique similaire d’etre conscients ce mettre œuvre ameliorations soins sante, particulier ciblant groupes d’âge pediatriques. En outre, l’information devrait etre fournie mesures devraient mises pour lutter contre vecteur Objetivo:  Evaluar incidencia serologica del ninos viviendo Brasil y evaluar los factores asociados. Metodos:  Se llevo cabo estudio serologico prospectivo una muestra con edades 0-3 anos edad. utilizo modelo logistico multinivel para identificar determinantes serologica. Resultados:  seroprevalencia era evaluados. segundo se detecto Una regresion logistica mostro asociacion estadisticamente significativa edad el lugar. Conclusion:  esta circulacion activa durante ninez temprana; consecuentemente, presentan anticuerpos heterotipicos tienen alto riesgo desarrollar fiebre hemorragica ya que secuencia e intensidad serotipos circulan ciudad son muy similares aquellos circulaban Janeiro-Brasil, Por lo tanto, autores recomiendan encarecidamente las autoridades sanitarias ciudades escenarios epidemiologicos sean conscientes riesgo, implementen mejoras cuidados sanitarios, particularmente enfocados grupos pediatricos. Adicionalmente deberia proveer informacion poblacion deberian implementar acciones controlar al vector.

参考文章(15)
TX Station, Stata Statistical Software: Release 7. 0 College Stata Corporation. ,(2001)
Elizabeth A. C. Newton, Paul Reiter, A model of the transmission of dengue fever with an evaluation of the impact of ultra-low volume (ULV) insecticide applications on dengue epidemics. American Journal of Tropical Medicine and Hygiene. ,vol. 47, pp. 709- 720 ,(1992) , 10.4269/AJTMH.1992.47.709
Maria da Gloria Teixeira, Mauricio L. Barreto, Maria da Conceicao N. Costa, Leila Denize A. Ferreira, Pedro F. C. Vasconcelos, Sandy Cairncross, Dynamics of dengue virus circulation: a silent epidemic in a complex urban area Tropical Medicine & International Health. ,vol. 7, pp. 757- 762 ,(2002) , 10.1046/J.1365-3156.2002.00930.X
Maria Gloria Teixeira, Maria Conceição N. Costa, Giovanini Coelho, Mauricio L. Barreto, Recent Shift in Age Pattern of Dengue Hemorrhagic Fever, Brazil Emerging Infectious Diseases. ,vol. 14, pp. 1663- 1663 ,(2008) , 10.3201/EID1410.071164
Giovanini E Coelho, Marcelo Nascimento Burattini, Maria da Glória Teixeira, Francisco Antonio Bezerra Coutinho, Eduardo Massad, Dynamics of the 2006/2007 dengue outbreak in Brazil Memorias Do Instituto Oswaldo Cruz. ,vol. 103, pp. 535- 539 ,(2008) , 10.1590/S0074-02762008000600004
Scott B. Halstead, Dengue in the Americas and Southeast Asia: do they differ? Revista Panamericana De Salud Publica-pan American Journal of Public Health. ,vol. 20, pp. 407- 415 ,(2006) , 10.1590/S1020-49892006001100007
Maria da Glória Teixeira, Maria da Conceição Nascimento Costa, Maurício Lima Barreto, Florisneide R. Barreto, Epidemiologia do dengue em Salvador-Bahia,1995-1999 Revista Da Sociedade Brasileira De Medicina Tropical. ,vol. 34, pp. 269- 274 ,(2001) , 10.1590/S0037-86822001000300007
Paulo Roberto Santana de Melo, Eliana Almeida Gomes Reis, Isolina Allen Ciuffo, Mônica Góes, Ronald Edward Blanton, Mitermayer Galvão dos Reis, The dynamics of dengue virus serotype 3 introduction and dispersion in the state of Bahia, Brazil Memorias Do Instituto Oswaldo Cruz. ,vol. 102, pp. 905- 912 ,(2007) , 10.1590/S0074-02762007000800003