Infektionen von Gefäßprothesen
作者： R. Kellersmann , O. Assadian , M. Zegelman
DOI: 10.1007/S00772-011-0949-4
关键词:
摘要: Infektionen von Gefasprothesen sind schwerwiegende Komplikationen rekonstruktiven gefaschirurgischen Eingriffen mit hoher konsekutiver Amputationsrate und Letalitat. Ihre Pathogenese ist multifaktoriell, dementsprechend existieren verschiedenste prophylaktische Ansatze. Neben den Grundsatzen der chirurgischen Asepsis werden zusatzliche Masnahmen zur Verbesserung hygienischen Bedingungen in perioperativen Phase angewandt. Die perioperative Antibiotikaprophylaxe diesem Zusammenhang das einzige Mittel, einen gewissen Evidenzgrad Bezug auf die Senkung Rate Protheseninfekten erreicht hat. Modifikationen Prothesen Steigerung ihrer Infektresistenz z. B. durch Rifampicin- oder Silberbindung seit Langem Gebrauch, Datenlage hierfur allerdings nicht eindeutig Gegenstand weiterer Untersuchungen. Ahnliches gilt fur lokale Antibiotikaapplikation Form Gentamicin-Kollagen-Schwammen. Neue Technologien antimikrobielle Substanzen hier Zukunft moglicherweise einmal komplett infektresistente Prothese schaffen.
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sci-hub.se 参考文章(69)
Braithwaite, Davies, Heather, Earnshaw, Early results of a randomized trial of rifampicin-bonded Dacron grafts for extra-anatomic vascular reconstruction. British Journal of Surgery. ,vol. 85, pp. 1378- 1381 ,(2003) , 10.1046/J.1365-2168.1998.00878.X
Joan Webster, Sonya Osborne, Preoperative bathing or showering with skin antiseptics to prevent surgical site infection Faculty of Health; Institute of Health and Biomedical Innovation. ,(2005)
Andrew Stewart, Paul S Eyers, Jonothan J Earnshaw, Prevention of infection in arterial reconstruction Cochrane Database of Systematic Reviews. ,(2006) , 10.1002/14651858.CD003073.PUB2
Holdsworth J, Treatment of infective and potentially infective complications of vascular bypass grafting using gentamicin with collagen sponge. Annals of The Royal College of Surgeons of England. ,vol. 81, pp. 166- 170 ,(1999)
Julian-Camill Harnoß, Lars-Ivo Partecke, Claus-Dieter Heidecke, Nils-Olaf Hübner, Axel Kramer, Ojan Assadian, Concentration of bacteria passing through puncture holes in surgical gloves American Journal of Infection Control. ,vol. 38, pp. 154- 158 ,(2010) , 10.1016/J.AJIC.2009.06.013
JJ Earnshaw, The current role of rifampicin-impregnated grafts: pragmatism versus science. European Journal of Vascular and Endovascular Surgery. ,vol. 20, pp. 409- 412 ,(2000) , 10.1053/EJVS.2000.1197
H. Gao, J. Sandermann, J. Prag, L. Lund, J.S. Lindholt, Prevention of Primary Vascular Graft Infection with Silver-Coated Polyester Graft in a Porcine Model European Journal of Vascular and Endovascular Surgery. ,vol. 39, pp. 472- 477 ,(2010) , 10.1016/J.EJVS.2009.11.023
C.J.L. Strachan, S.W.B. Newsom, T.R. Ashton, The clinical use of an antibiotic-bonded graft European Journal of Vascular Surgery. ,vol. 5, pp. 627- 632 ,(1991) , 10.1016/S0950-821X(05)80896-5
Dennis F. Bandyk, Vascular surgical site infection: risk factors and preventive measures Seminars in Vascular Surgery. ,vol. 21, pp. 119- 123 ,(2008) , 10.1053/J.SEMVASCSURG.2008.05.008
S. Hardman, A. Cope, A. Swann, P.R.F. Bell, A.R. Naylor, P.D. Hayes, An in vitro model to compare the antimicrobial activity of silver-coated versus rifampicin-soaked vascular grafts. Annals of Vascular Surgery. ,vol. 18, pp. 308- 313 ,(2004) , 10.1007/S10016-004-0042-5