Molecular epidemiology of extended-spectrum beta-lactamase-producing Enterobacteriaceae isolated from environmental and clinical specimens in a cardiac surgery intensive care unit.
作者： Guillaume Kac , Isabelle Podglajen , Sabine Vaupré , Nathalie Colardelle , Annie Buu-Hoï
DOI: 10.1086/502308
关键词:
摘要: OBJECTIVES: To investigate environmental contamination by extended-spectrum beta-lactamase-producing Enterobacteriaceae and to perform a comparative molecular analysis of clinical strains. SETTING: A 17-bed cardiac surgery intensive care unit 480-bed university teaching hospital. METHODS: Following an outbreak Enterobacteriaceae, survey revealed extensive the environment (particularly faucets, sink drains, joints countertops) Enterobacteriaceae. Environmental strains were compared with pulsed-field gel electrophoresis randomly amplified polymorphic DNA. RESULTS: total 62 belonging 4 species analyzed 43 obtained from 34 patients. Comparative identical or closely related patterns (3 Klebsiella oxytoca 1 Enterobacter cloacae) between CONCLUSIONS: Moist surfaces may serve as sources multiply resistant in unit. Identification disinfection such therefore be helpful prevention control outbreaks.
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