The Effect of Four Coffee types on Normotensive rats and Normal/Hypertensive Human Volunteers

作者: Amani S. Awaad , G. A. Soliman , Mounerah R. Al-Outhman , Ibtehaj F. Al-Shdoukhi , Rawan S. Al-Nafisah

DOI: 10.1002/PTR.3333

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摘要: Coffee is a commonly consumed beverage. The purpose of this study was to determine the effect four coffee types on blood pressure (BP). caffeine percentage tested one cup (250 mL) each type (Arabian, Turkish, American and an instant preparation) using two methods. 65 adult male rats 400 healthy human volunteers were used in study. Normotensive treated orally with single dose normal saline varying coffee. mildly hypertensive administered any separately. Tail cuff strain-gauge plethysmograph measure systolic (SBP), diastolic (DBP) heart rate (HR) rats, volunteers, respectively before 0.5, 1.0, 1.5, 2 h post administration. mean arterial (MAP) calculated mathematically SBP DBP. alkaloidal different showed presence variable contents amount active materials. that Arabian, all have potential cause BP lowering effect. Variable antimicrobial activities recorded for when bacteria. Copyright © 2010 John Wiley & Sons, Ltd.

参考文章(28)
Qin Wan-zhang, Lin Jian, Advance of the research on Tripterygium Wilfordii Hook f. to a new height. Chinese Journal of Integrative Medicine. ,vol. 11, pp. 87- 88 ,(2005) , 10.1007/BF02836462
R D Buñag, Validation in awake rats of a tail-cuff method for measuring systolic pressure Journal of Applied Physiology. ,vol. 34, pp. 279- 282 ,(1973) , 10.1152/JAPPL.1973.34.2.279
Gregory Y H Lip, Gareth Beevers, Eoin O'Brien, Blood Pressure Measurement ,(1990)
Kazuo FUNATSU, Takeshi YAMASHITA, Haruo NAKAMURA, Effect of coffee intake on blood pressure in male habitual alcohol drinkers Hypertension Research. ,vol. 28, pp. 521- 527 ,(2005) , 10.1291/HYPRES.28.521
Gwendolyn A. Pincomb, William R. Lovallo, Richard B. Passey, Michael F. Wilson, Effect of behavior state on caffeine's ability to alter blood pressure. American Journal of Cardiology. ,vol. 61, pp. 798- 802 ,(1988) , 10.1016/0002-9149(88)91069-7
David John Finney, Statistical method in biological assay. Statistical method in biological assay.. ,(1952)
Marilyn C Cornelis, Ahmed El-Sohemy, Coffee, caffeine, and coronary heart disease. Current Opinion in Lipidology. ,vol. 18, pp. 13- 19 ,(2007) , 10.1097/MOL.0B013E3280127B04
V. M. Hawthorne, D. A. Greaves, D. G. Beevers, Blood Pressure in a Scottish Town BMJ. ,vol. 3, pp. 600- 603 ,(1974) , 10.1136/BMJ.3.5931.600
Peter J. Green, Robert Kirby, Jerry Suls, The effects of caffeine on blood pressure and heart rate: A review Annals of Behavioral Medicine. ,vol. 18, pp. 201- 216 ,(1996) , 10.1007/BF02883398