Predictors of acute respiratory distress syndrome in patients with paraquat intoxication.

摘要: Introduction Paraquat poisoning is characterized by acute lung injury, pulmonary fibrosis, respiratory failure, and multi-organ resulting in a high rate of mortality morbidity. The objectives this study were to identify predictors distress syndrome (ARDS) cases paraquat determine the association between these parameters. Materials Methods In total, 187 patients referred for management intentional ingestion 2000 2010. Demographic, clinical, laboratory data recorded. Sequential organ failure assessment (SOFA) Acute Kidney Injury Network (AKIN) scores collected, ARDS analyzed. Results The overall entire population was 54% (101/187). Furthermore, higher than non-ARDS (80% vs. 43.80%, P<0.001). Additionally, not only had AKIN48-h (P<0.009), SOFA48-h (P<0.001), time ARDS/nadir PaO2 (P=0.008) but also suffered from lower nadir AaDO2 eGFR (P=0.001) compared those patients. Moreover, pneumomediastinum episodes more frequent (P<0.001). A multivariate Cox regression model revealed that blood concentrations (P=0.001), steroid cyclophosphamide pulse therapies (P=0.024) significant ARDS. cumulative survival rates differed significantly (P<0.001) with <3 ≥3, sensitivity 95.8%, specificity 58.4%, correctness 67.6%. Finally, area under receiver operating characteristic (AUROC) analysis showed better discriminatory power (P=0.01) predicting Conclusions analytical results indicate scores, concentrations, are associated complications after intoxication.