Polyaxonal myelination in developing dystrophic and normal mouse nerves.

摘要: Myelin-forming Schwann cells in the peripheral nervous system characteristically surround and myelinate only single axons. Polyaxonal myelination is an anomaly of this one-to-one relationship whereby one normal-appearing cell myelinates multiple We examined ventral roots proximal sciatic posterior tibial nerves developing normal mice dy2J/dy2J dystrophic with failure myelination. was a rare feature nerves. Examples polyaxonal were observed six times more often than most abundant could result from either axonal or Schwann-cell abnormality, it may be nonspecific response uncommitted to early