Tellurium-induced myelinopathy in adult rats.
作者： G�rard Said , Serge Duckett
关键词: Anatomy 、 Nerve fiber 、 Paralysis 、 Brachial plexus 、 Myelinopathy 、 Spinal Roots 、 Electron microscope 、 Myelin 、 Pathology 、 Remyelination 、 Medicine
摘要: Tellurium is known to induce a neuropathy in young rats but not adult rats. In the present study were fed diet containing 1.25% tellurium every day for 30 days. By end of this period, moved with difficulty did show paralysis. Study teased nerve fiber preparations conjunction light and electron microscopy revealed myelin abnormalities consisting bubbling, segmental demyelination, remyelination. some animals, these had patchy distribution, affecting several adjoining fibers sciatic nerves, brachial plexus, spinal roots. The intramyelinic edema sometimes was associated splitting axons.
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