A critical new pathway for toxin secretion

作者: Timothy L. Yahr

DOI: 10.1056/NEJMCIBR063931

关键词:

摘要: A new secretion system in Vibrio cholerae, Pseudomonas aeruginosa, and other gram-negative bacteria represents a potential target for vaccine development.

参考文章(4)
S. Pukatzki, A. T. Ma, D. Sturtevant, B. Krastins, D. Sarracino, W. C. Nelson, J. F. Heidelberg, J. J. Mekalanos, Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 1528- 1533 ,(2006) , 10.1073/PNAS.0510322103
Joseph D Mougous, Marianne E Cuff, Stefan Raunser, Aimee Shen, Min Zhou, Casey A Gifford, Andrew L Goodman, Grazyna Joachimiak, Claudia L Ordoñez, Stephen Lory, Thomas Walz, Andrzej Joachimiak, John J Mekalanos, A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus Science. ,vol. 312, pp. 1526- 1530 ,(2006) , 10.1126/SCIENCE.1128393
Eric Potvin, Dario E. Lehoux, Irena Kukavica-Ibrulj, Karine L. Richard, Fran��ois Sanschagrin, Gee W. Lau, Roger C. Levesque, In vivo functional genomics of Pseudomonas aeruginosa for high‐throughput screening of new virulence factors and antibacterial targets Environmental Microbiology. ,vol. 5, pp. 1294- 1308 ,(2003) , 10.1046/J.1462-2920.2003.00542.X
R. Nordfelth, A. M. Kauppi, H. A. Norberg, H. Wolf-Watz, M. Elofsson, Small-Molecule Inhibitors Specifically Targeting Type III Secretion Infection and Immunity. ,vol. 73, pp. 3104- 3114 ,(2005) , 10.1128/IAI.73.5.3104-3114.2005