Novel ido inhibitors and methods of use
作者： George C. Prendergast , Alexander J. Muller , William Malachowski , James B. Duhadaway
DOI:
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摘要: Novel substituted indoyl derivatives having IDOinhibitor activity are disclosed which useful in the treatment of cancer a patient need such treatment. The compounds may be used concurrently or sequentially. Pharmaceutical compositions comprising novel also disclosed.
lens.org参考文章(13)
Marian Sabol, Peter Kutschy, Leonard Siegfried, A Miroššay, M Suchý, Helga Hrbkova, Milan Dzurilla, R Marušková, Julia Starkova, Edita Paulikova, None, Cytotoxic effect of cruciferous phytoalexins against murine L1210 leukemia and B16 melanoma. Biologia (Bratislava). ,vol. 55, pp. 701- 707 ,(2000)
Gregory D. Cuny, Junying Yuan, Alexei Degterev, Prakash Jagtap, Inhibitors of cellular necrosis ,(2004)
James B. Duhadaway, George C. Prendergast, William Malachowski, Alexander J. Muller, Novel methods for the treatment of cancer ,(2004)
James B. DuHadaway, George C. Prendergast, William Malachowski, Alexander J. Muller, IDO inhibitors and methods of use ,(2010)
Karsten Nordhoff, Ute Bank, Frank Striggow, Michael Taeger, Siegfried Ansorge, Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases ,(2004)
Rajendra G. Mehta, Jinfang Liu, Andreas Constantinou, Cathy F. Thomas, Michael Hawthorne, Min You, Clarissa Gerhäuser, John M. Pezzuto, Richard C. Moon, Robert M. Moriarty, Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage Carcinogenesis. ,vol. 16, pp. 399- 404 ,(1995) , 10.1093/CARCIN/16.2.399
A. C. PETERSON, A. J. LA LOGGIA, L. K. HAMAKER, R. A. AREND, P. L. FISETTE, Y. OZAKI, J. A. WILL, R. R. BROWN, J. M. COOK, Evaluation of Substituted β‐Carbolines as Noncompetitive Indolamine 2,3‐Dioxygenase Inhibitors. ChemInform. ,vol. 25, ,(1994) , 10.1002/CHIN.199435294
Junying Yuan, Alexei Degterev, Timothy J. Mitchison, Small molecule inhibitors of necrosis ,(2000)
Karsten Nordhoff, Ute Bank, Frank Striggow, Siegfried Ansorge, Michael Tager, Novel dipeptidyl peptidase iv inhibitors used for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases ,(2004)
David P M Pleynet, Lyle W Spruce, Magnus Pfahl, Torsten R Wiemann, Catherine Tachdjian, Jason B Ibarra, Andrea Fanjul, Hussein A Al-Shamma, Heterocyclic derivatives for the treatment of cancer and other proliferative diseases ,(2002)