Identification of a Higher‐Order Organozincate Intermediate Involved in Negishi Cross‐Coupling Reactions by Mass Spectrometry and NMR Spectroscopy
作者： Howard N. Hunter , Niloufar Hadei , Voislav Blagojevic , Pascal Patschinski , George T. Achonduh
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摘要: Negishi cross-coupling reactions were analyzed in solution by mass spectrometry and NMR spectroscopy to identify both the effect of LiBr as an additive well purpose 3-dimethyl-2-imidazolidinone (DMI) a co-solvent. The results suggest that main role DMI is facilitate higher order bromozincate formation during addition LiBr.
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