摘要: Purpose of reviewThis review provides an overview the immunological effects commonly used analgesic opioid drugs with particular emphasis on human studies, final aim to highlight their potential clinical relevance.Recent findingsThe immunomodulatory morphine have been chara
sci-hub.se 参考文章(42)
Benzion Beilin, Galina Grinevich, Israel Z. Yardeni, Hanna Bessler, Tramadol does not impair the phagocytic capacity of human peripheral blood cells. Canadian Journal of Anaesthesia-journal Canadien D Anesthesie. ,vol. 52, pp. 1035- 1039 ,(2005) , 10.1007/BF03021601
John F. Hansbrough, Edward M. Bender, Ramon Zapata-Sirvent, Julie Anderson, Altered helper and suppressor lymphocyte populations in surgical patients: A measure of postoperative immunosuppression American Journal of Surgery. ,vol. 148, pp. 303- 307 ,(1984) , 10.1016/0002-9610(84)90459-8
Sabita Roy, Jinghua Wang, Richard Charboneau, Horace H. Loh, Roderick A. Barke, Morphine induces CD4+ T cell IL-4 expression through an adenylyl cyclase mechanism independent of the protein kinase A pathway. Journal of Immunology. ,vol. 175, pp. 6361- 6367 ,(2005) , 10.4049/JIMMUNOL.175.10.6361
Jinghua Wang, Roderick A. Barke, Sabita Roy, Transcriptional and Epigenetic Regulation of Interleukin-2 Gene in Activated T Cells by Morphine Journal of Biological Chemistry. ,vol. 282, pp. 7164- 7171 ,(2007) , 10.1074/JBC.M604367200
Roland Jacobs, Matthias Karst, Dirk Scheinichen, Carmine Bevilacqua, Udo Schneider, Jörn Heine, Manfred Schedlowski, Reinhold E Schmidt, Effects of fentanyl on cellular immune functions in man International Journal of Immunopharmacology. ,vol. 21, pp. 445- 454 ,(1999) , 10.1016/S0192-0561(99)00025-9
Jinghua Wang, Roderick A. Barke, Richard Charboneau, Horace H. Loh, Sabita Roy, Morphine Negatively Regulates Interferon-γ Promoter Activity in Activated Murine T Cells through Two Distinct Cyclic AMP-dependent Pathways Journal of Biological Chemistry. ,vol. 278, pp. 37622- 37631 ,(2003) , 10.1074/JBC.M301224200
Cataldo Martucci, Silvia Franchi, Donatella Lattuada, Alberto E. Panerai, Paola Sacerdote, Differential involvement of RelB in morphine-induced modulation of chemotaxis, NO, and cytokine production in murine macrophages and lymphocytes. Journal of Leukocyte Biology. ,vol. 81, pp. 344- 354 ,(2007) , 10.1189/JLB.0406237
Saori Hashiguchi, Hiroshi Morisaki, Yoshifumi Kotake, Junzo Takeda, Effects of morphine and its metabolites on immune function in advanced cancer patients Journal of Clinical Anesthesia. ,vol. 17, pp. 575- 580 ,(2005) , 10.1016/J.JCLINANE.2005.03.004
Claire Gavériaux-Ruff, Hans WD Matthes, Jean Peluso, Brigitte L Kieffer, Abolition of Morphine-Immunosuppression in Mice Lacking the μ -opioid Receptor Gene Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 6326- 6330 ,(1998) , 10.1073/PNAS.95.11.6326
Wendy Jeal, Paul Benfield, Transdermal fentanyl. A review of its pharmacological properties and therapeutic efficacy in pain control. Drugs. ,vol. 53, pp. 109- 138 ,(1997) , 10.2165/00003495-199753010-00011