Studies on the mutagenic action of chemical and physical agencies on yeasts

摘要: 1. Investigations in this laboratory indicated that polyploidogens are also mutagenic and mutagens may induce polyploidy. Doubling of the chromosomes leading to viable tetraploid races is sporadic such an induction was observed after ultra-violet irradiation. 2. Experiments were therefore carried out confirm suspicion a doubling chromosome complement irradiation be as unpredictable specific gene mutation. 3. Photographs giant colonies treated control material presented. 4. The evidence recorded paper confirmed tetraploidy being conditioned by mutation induced mutations sporadic, treatment with rays does not always lead production tetraploidy. 5. The existence multiple alleles at locus governing nature sculpturing colony confirmed. 6. Ultra-violet has immediate well delayed effects unpredictable. 7. A theory mode action various biologically effective physical chemical agents on living organisms considered.