Mucin abnormality of colonic mucosa in ulcerative colitis associated with carcinoma and/or dysplasia.

作者: S. Agawa , T. Muto , Y. Morioka

DOI: 10.1007/BF02564892

关键词:

摘要: Twenty cases of resected specimens carcinoma and/or dysplasia complicating ulcerative colitis were histochemically investigated by the periodic acid-thionin Schiff/potassium hydroxide/periodic acid-Schiff (PAT/KOH/PAS) staining method to see mucin characteristics carcinoma, dysplasia, and background mucosa these lesions. As a control, 11 without dysplastic changes 26 colonic examined also. All in stained blue, whereas normal red 65 percent. In 14 20 with appeared hematoxylin eosin staining, but showed mosaic pattern PAT/KOH/PAS. However, only two none flat colorectal pattern. From observations it was concluded that PAT/KOH/PAS could be useful as histochemical marker premalignant change longstanding colitis.

参考文章(23)
M.G. Cook, J.C. Goligher, Carcinoma and Epithelial Dysplasia Complicating Ulcerative Colitis Gastroenterology. ,vol. 68, pp. 1127- 1136 ,(1975) , 10.1016/S0016-5085(75)80225-3
Moshe B. Goldgraber, Joseph B. Kirsner, Carcinoma of the colon in ulcerative colitis Cancer. ,vol. 17, pp. 657- 665 ,(1964) , 10.1002/1097-0142(196405)17:5<657::AID-CNCR2820170515>3.0.CO;2-7
Nagy A. Habib, Peter M. Dawson, Thomas Krausz, Margaret A. Blount, David Kersten, Christopher B. Wood, A study of histochemical changes in mucus from patients with ulcerative colitis, Crohn's disease, and diverticular disease of the colon. Diseases of The Colon & Rectum. ,vol. 29, pp. 15- 17 ,(1986) , 10.1007/BF02555277
BURRILL B. CROHN, HERMAN ROSENBERG, The sigmoidoscopic picture of chronic ulcerative colitis (non-specific) The American Journal of the Medical Sciences. ,vol. 170, pp. 220- 227 ,(1925) , 10.1097/00000441-192508010-00006
B C Morson, L S Pang, Rectal biopsy as an aid to cancer control in ulcerative colitis. Gut. ,vol. 8, pp. 423- 434 ,(1967) , 10.1136/GUT.8.5.423
C F Culling, P E Reid, A J Worth, W L Dunn, A new histochemical technique of use in the interpretation and diagnosis of adenocarcinoma and villous lesions in the large intestine. Journal of Clinical Pathology. ,vol. 30, pp. 1056- 1062 ,(1977) , 10.1136/JCP.30.11.1056
C F Culling, P E Reid, W L Dunn, A new histochemical method for the identification and visualization of both side chain acylated and nonacylated sialic acids. Journal of Histochemistry and Cytochemistry. ,vol. 24, pp. 1225- 1230 ,(1976) , 10.1177/24.12.187689