Routine but risky: A multi-centre analysis of the outcomes of cranioplasty in the Northeast of England

摘要: Cranioplasty is undertaken as a routine secondary operation following craniectomy. At time when decompressive craniectomy being evaluated by several large trials, we aimed to evaluate the morbidity associated with cranioplasty and investigate its potential effect on outcome. The outcomes of 166 patients undergoing at two centres in United Kingdom between June 2006 September 2011 were retrospectively analysed. Outcome measures included mortality, functional outcome determined modified Rankin score (mRS) last follow-up. A logistic regression analysis was performed model predict determinants related neurological cranioplasty. Sixty-seven out (40.4 %) experienced least one complication during median follow-up 15 months (inter-quartile range 5-38 months). Thirty six (21.7 %) developed infection requiring antibiotics, 27 (16.3 %) removal Nine 25 (36 %) bi-frontal defects an whereas 21 153 (16.4 %) defect other than (Chi square p = 0.009). Further surgery groups required 16.4 % 11.7, % respectively. Pseudomeningocoele (9 %), seizures (8.4 %) poor cosmesis (7.2 %) also commonly observed. Logistic identified initial (p < 0.03), mRS (p < 0.0001) complications (p < 0.04) predictive Age timing not harbours significant morbidity, risk that appears be higher bifrontal defect. influence subsequent cranioplasty, early or late, after does impact ultimate These findings should considered making decisions relating