BORON CLUSTER BONDED PEPTIDE COMPOUND
作者： Nishiyama Nobuhiro , Kataoka Kazunori , Cabral Horacio , Mi Peng , Takemoto Hiroyasu
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摘要: The purpose of the present invention is to provide a novel boron-containing compound which exhibits excellent accumulation in cancers due EPR effect, does not take nanoparticle form and therefore high penetration into tumor tissue, efficiently taken up cancer cells. relates peptide having boron cluster polyether, as constituent amino acid an selected from neutral acids acidic acids, or salts such compound.
lens.org 参考文章(6)
Ryosuke Tanaka, Yasuki Kato, Hiroyuki Saito, Mitsunori Harada, Katsutoshi Kobayashi, Pharmaceutical composition containing block copolymer comprising boric acid compound ,(2012)
Gabrio Roncucci, Moira Municchi, Giulio Jori, Giacomo Chiti, Donata Dei, Clara Fabris, Francesca Giuntini, Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof ,(2004)
Chieko Seno, Masayuki Kitagawa, Polymer conjugate of physiologically active substance ,(2009)
Peng Mi, Hironobu Yanagie, Novriana Dewi, Hung-Chi Yen, Xueying Liu, Minoru Suzuki, Yoshinori Sakurai, Koji Ono, Hiroyuki Takahashi, Horacio Cabral, Kazunori Kataoka, Nobuhiro Nishiyama, Block copolymer-boron cluster conjugate for effective boron neutron capture therapy of solid tumors. Journal of Controlled Release. ,vol. 254, pp. 1- 9 ,(2017) , 10.1016/J.JCONREL.2017.03.036
諭吉 堀口, Yukichi Horiguchi, 幸夫 長崎, Koji Ono, 松村 明, 長崎 幸夫, Minoru Suzuki, Yukio Nagasaki, 啓 中井, 明 松村, Shinu Ko, Akira Matsumura, Hiroshi Nakai, 振宇 高, 鈴木 実, 公二 小野, 実 鈴木, Polymeric boron compound and its use ,(2013)
Nakamura Hiroyuki, PHARMACEUTICAL COMPOSITION CONTAINING CONJUGATE OF BORON-CONTAINING COMPOUND AND PROTEIN ,(2017)