Effect of acidic pH on PLGA microsphere degradation and release
作者： Banu S. Zolnik , Diane J. Burgess
DOI: 10.1016/J.JCONREL.2007.05.034
关键词:
摘要: … PLGA microspheres to determine how such media might affect polymer degradation. In particular, the effect on microsphere … Accordingly, a comprehensive microsphere characterization …
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sci-hub.se 参考文章(27)
Anna Shenderova, Thomas G. Burke, Steven P. Schwendeman, The acidic microclimate in poly(lactide-co-glycolide) microspheres stabilizes camptothecins. Pharmaceutical Research. ,vol. 16, pp. 241- 248 ,(1999) , 10.1023/A:1018876308346
Karen Fu, Daniel W. Pack, Alexander M. Klibanov, Robert Langer, Visual Evidence of Acidic Environment Within Degrading Poly(lactic-co-glycolic acid) (PLGA) Microspheres Pharmaceutical Research. ,vol. 17, pp. 100- 106 ,(2000) , 10.1023/A:1007582911958
Richard T Liggins, Helen M Burt, Paclitaxel loaded poly(L-lactic acid) (PLLA) microspheres. II. The effect of processing parameters on microsphere morphology and drug release kinetics. International Journal of Pharmaceutics. ,vol. 281, pp. 103- 106 ,(2004) , 10.1016/J.IJPHARM.2004.05.027
Anette Brunner, Karsten Mäder, Achim Göpferich, pH and osmotic pressure inside biodegradable microspheres during erosion. Pharmaceutical Research. ,vol. 16, pp. 847- 853 ,(1999) , 10.1023/A:1018822002353
R. K. Kulkarni, E. G. Moore, A. F. Hegyeli, Fred Leonard, Biodegradable poly(lactic acid) polymers Journal of Biomedical Materials Research. ,vol. 5, pp. 169- 181 ,(1971) , 10.1002/JBM.820050305
Tae Gwan Park, Degradation of poly(d,l-lactic acid) microspheres: effect of molecular weight Journal of Controlled Release. ,vol. 30, pp. 161- 173 ,(1994) , 10.1016/0168-3659(94)90263-1
Tae Gwan Park, Degradation of poly(lactic-co-glycolic acid) microspheres: effect of copolymer composition Biomaterials. ,vol. 16, pp. 1123- 1130 ,(1995) , 10.1016/0142-9612(95)93575-X
L. RAMIREZ, Biodegradable poly(DL-lactic-co-glycolic acid) microspheres containing tetracaine hydrochloride. In-vitro release profile. Journal of Microencapsulation. ,vol. 16, pp. 105- 115 ,(1999) , 10.1080/026520499289356
N. Faisant, J. Akiki, F. Siepmann, J.P. Benoit, J. Siepmann, Effects of the type of release medium on drug release from PLGA-based microparticles: Experiment and theory International Journal of Pharmaceutics. ,vol. 314, pp. 189- 197 ,(2006) , 10.1016/J.IJPHARM.2005.07.030