作者: Chiara Dionigi , Tamara Posati , Valentina Benfenati , Anna Sagnella , Assunta Pistone
DOI: 10.1039/C3TB21172J
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摘要: Silk fibroin (SF), a protein core fibre from the silkworm Bombyx mori, has huge potential to become sustainable, biocompatible, and biodegradable material platform that can pave way towards replacement of plastic in fabrication bio-derived materials for variety technological biomedical applications. SF remarkable mechanical flexibility, controllable biodegradability, biocompatibility is capable drug/doping inclusion, stabilization release. However, dielectric properties limit its as direct bioelectronic interface devices intended control bioelectrical activity cell regenerative purposes. In this work, novel wet templating method proposed generate nanostructured, conductive Fibroin (SF) composite films. We combine unusual SF, such properties, convenience with electrical conductivity stiffness Single Walled Carbon Nanotubes (SWCNTs). The presented SF–SWCNT displays periodic architecture where SWCNTs are regularly homogeneously distributed matrix. morphological chemo-physical nanocomposite analysed defined by SEM, Raman Spectroscopy, ATR-IR, UFM contact angle analyses. Notably, film conductive, showing additional functionality compared bare film. Finally, biocompatible enables growth primary rat Dorsal Root Ganglion (DRG) neurons. Collectively our results demonstrate robust be fabricated using method, paving development silk-based electronic use