作者: Camille Lassale , Marc J. Gunter , Dora Romaguera , Linda M. Peelen , Yvonne T. Van der Schouw
DOI: 10.1371/JOURNAL.PONE.0159025
关键词:
摘要: Scores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value risk prediction has been little examined. The objective was assess and compare the association predictive performance 10 scores on 10-year all-cause, CVD cancer mortality 451,256 healthy participants European Prospective Investigation into Cancer Nutrition, followed-up for a median 12.8y. All dietary studied showed significant inverse associations with all outcomes. range HRs (95% CI) top vs. lowest quartile composite model including non-invasive factors (age, sex, smoking, body mass index, education, physical activity study centre) 0.75 (0.72-0.79) 0.88 (0.84-0.92) 0.76 (0.69-0.83) 0.84 (0.76-0.92) 0.78 (0.73-0.83) 0.91 (0.85-0.97) mortality. Models alone low discrimination, but models also age, sex other good discrimination calibration, which varied between different Mean C-statistic full 0.73, 0.80 0.71 Dietary poor when used isolation display ability combination common factors.