Effect of the probiotic Saccharomyces cerevisiae on ligature‐induced periodontitis in rats
作者： V. G. Garcia , L. R. Knoll , M. Longo , V. C. N. Novaes , N. Z. Assem
DOI: 10.1111/JRE.12274
关键词:
摘要: Background and Objective This study assessed the effects of local use Saccharomyces cerevisiae as monotherapy an adjuvant to mechanical treatment ligature-induced periodontitis in rats. Material Methods Periodontitis was induced 72 rats via installation a ligature around mandibular first molar. After 7 d, removed were placed one following groups: no (C; n = 18); scaling root planing (SRP; irrigation with probiotics (PRO; SRP followed by (SRP/PRO; n = 18). Six from each group killed at 7, 15 30 d. The histological characteristics, alveolar bone loss (ABL) immunolabeling tumor necrosis factor alpha (TNF-α), interleukin-1beta (IL-1β), interleukin-10 (IL-10) TRAP on furcation area molar assessed. Results The PRO showed features acceleration tissue-repair process during entire experiment. On day 15, there less ABL SRP/PRO compared C group. There fewer TRAP-positive cells groups immunostaining for TNF-α IL-1β However, more IL-10 15. Conclusion Local probiotic did not result any adverse periodontal tissues. When used or adjuvant, effective controlling rats.
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