A specific complement-fixation test for human hepatitis a employing CR326 virus antigen. Diagnosis and epidemiology.

摘要: SummaryA specific diagnostic complement-fixation test for hepatitis A antibody in human serum was described employing livers of marmosets infected with CR326 strain virus. Persons A, but not B, developed CF shortly after the onset illness and this persisted thereafter. Good agreement noted development neutralizing antibodies cases. Hepatitis shown to occur a person B antigenemia occurred persons antibody. Most who were tested, none those increased anticomplementary activity their sera at time illness. At least one patient against normal liver that persisted. The possible implications relation pathogenesis nonspecific tests discussed. limited epidemiologic study family outbreak...