Efficacy of a Second Line Luteinizing Hormone-Releasing Hormone Agonist After Advanced Prostate Cancer Biochemical Recurrence

摘要: Purpose: Men with castrate resistant prostate cancer have limited treatment options. Although luteinizing hormone-releasing hormone agonists are in the same class, they slightly different their pharmacology. We determined whether rechallenging patients cancer, who were receiving a analogue but had progression, (goserelin or leuprolide acetate) would result specific antigen response. Secondary objectives to calculate PSA response and determine sequence order impacted response.Materials Methods: performed retrospective, ethics approved review of records at multiple institutions received acetate), experienced as measured by 2 consecutive increases, rechallenged other analogue...