Heterotopically induced bone marrow formation: morphology and transplantation.

摘要: Following heterotopic osteogenesis by implantation of xenogeneic epithelia, established human amnion cell lines FL and WISH, isolated transitional epithelium dogs in mice, biogenesis hematopoietic tissue among the induced bone ossicles was observed. Precursors mature forms erythroid, granuloid, lymphoid megakaryocytic series were found marrow. The concentration lymphocytes marrow higher that erythropoietic cells lower as compared with orthotopic femur yield myeloid varied from 0.31 to 14.5 X 10(6) per nodule, when uroepithelium used an inductor. contained hemopoietic stem similar medullar protected lethally irradiated syngeneic recipients same doses