Vps74p controls Golgi size in an Arf1-dependent manner
作者： Prasanna Iyer , Madhura Bhave , Bhawik Kumar Jain , Sudeshna RoyChowdhury , Dibyendu Bhattacharyya
关键词:
摘要: The oncogene GOLPH3 is implicated in Golgi size regulation, a function yet to be experimentally linked its PI4P effector or the cisternal maturation general. Moreover, yeast homolog, Vps74p not regulation. Our results indicate that VPS74 deletion increases late and frequencies, destabilizes gradient budding yeast. Overexpression of Arf1 can suppress this enlargement increased frequency phenotype ∆vps74. ∆arf1 alters distribution along stacks. We conclude Vps74p, downstream Arf1, regulates by altering maintaining compartments.
sci-hub.se 参考文章(42)
Ken Sato, Takashi Ueda, Akihiko Nakano, The Arabidopsis thaliana RER1 gene family: its potential role in the endoplasmic reticulum localization of membrane proteins. Plant Molecular Biology. ,vol. 41, pp. 815- 824 ,(1999) , 10.1023/A:1006329828395
Christiane Walch-Solimena, Peter Novick, The yeast phosphatidylinositol-4-OH kinase pik1 regulates secretion at the Golgi. Nature Cell Biology. ,vol. 1, pp. 523- 525 ,(1999) , 10.1038/70319
Linna Tu, Lu Chen, David K. Banfield, A conserved N-terminal arginine-motif in GOLPH3-family proteins mediates binding to coatomer. Traffic. ,vol. 13, pp. 1496- 1507 ,(2012) , 10.1111/J.1600-0854.2012.01403.X
Anna Godi, Paolo Pertile, Rachel Meyers, Pierfrancesco Marra, Giuseppe Di Tullio, Cristiano Iurisci, Alberto Luini, Daniela Corda, Maria Antonietta De Matteis, ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex. Nature Cell Biology. ,vol. 1, pp. 280- 287 ,(1999) , 10.1038/12993
Vikram Ghugtyal, Rocio Garcia-Rodas, Agnese Seminara, Sébastien Schaub, Martine Bassilana, Robert Alan Arkowitz, Phosphatidylinositol-4-phosphate-dependent membrane traffic is critical for fungal filamentous growth Proceedings of the National Academy of Sciences. ,vol. 112, pp. 8644- 8649 ,(2015) , 10.1073/PNAS.1504259112
Ulrich Güldener, Susanne Heck, Thomas Fiedler, Jens Beinhauer, Johannes H Hegemann, A New Efficient Gene Disruption Cassette for Repeated Use in Budding Yeast Nucleic Acids Research. ,vol. 24, pp. 2519- 2524 ,(1996) , 10.1093/NAR/24.13.2519
R. Beck, Z. Sun, F. Adolf, C. Rutz, J. Bassler, K. Wild, I. Sinning, E. Hurt, B. Brugger, J. Bethune, F. Wieland, Membrane curvature induced by Arf1-GTP is essential for vesicle formation. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 11731- 11736 ,(2008) , 10.1073/PNAS.0805182105
Yvonne Gloor, Mario Schöne, Bianca Habermann, Ebru Ercan, Mike Beck, Grit Weselek, Thomas Müller-Reichert, Christiane Walch-Solimena, Interaction between Sec7p and Pik1p: the first clue for the regulation of a coincidence detection signal. European Journal of Cell Biology. ,vol. 89, pp. 575- 583 ,(2010) , 10.1016/J.EJCB.2010.02.004
Jez G. Carlton, Peter J. Cullen, Coincidence detection in phosphoinositide signaling Trends in Cell Biology. ,vol. 15, pp. 540- 547 ,(2005) , 10.1016/J.TCB.2005.08.005
Giancarlo Costaguta, Gregory S. Payne, Phosphoinositide-mediated clathrin adaptor progression at the trans -Golgi network Nature Cell Biology. ,vol. 14, pp. 239- 248 ,(2012) , 10.1038/NCB2427