Antisense modulation of tumor necrosis factor receptor 2 expression
作者： C. Frank Bennett , Andrew T. Watt
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摘要: Antisense compounds, compositions and methods are provided for modulating the expression of Tumor Necrosis Factor Receptor 2. The comprise antisense particularly oligonucleotides, targeted to nucleic acids encoding Methods using these compounds modulation 2 treatment diseases associated with provided.
lens.org参考文章(21)
W. Michael Flanagan, Richard W. Wagner, Deborah Grant, Kuei-Ying Lin, Mark D. Matteucci, Cellular penetration and antisense activity by a phenoxazine-substituted heptanucleotide Nature Biotechnology. ,vol. 17, pp. 48- 52 ,(1999) , 10.1038/5220
Oliver Kemper, Peter Kuhnert, David Wallach, Gotz Ehrhardt, P75 TNF receptor promoters ,(1995)
Douglas W Green, Haeri Roh, James Pippin, Jeffrey A Drebin, Antisense oligonucleotides: an evolving technology for the modulation of gene expression in human disease. Journal of The American College of Surgeons. ,vol. 191, pp. 93- 105 ,(2000) , 10.1016/S1072-7515(00)00305-7
Edgardo Baracchini, C. Frank Bennett, Nicholas M. Dean, Antisense oligonucleotide modulation of multidrug resistance-associated protein ,(1997)
Graig C. Suvannavejh, Hae-Ock Lee, Josette Padilla, Mauro C. Dal Canto, Terrance A. Barrett, Stephen D. Miller, Divergent Roles for p55 and p75 Tumor Necrosis Factor Receptors in the Pathogenesis of MOG35-55-Induced Experimental Autoimmune Encephalomyelitis Cellular Immunology. ,vol. 205, pp. 24- 33 ,(2000) , 10.1006/CIMM.2000.1706
Yong Shen, Rena Li, Kazumi Shiosaki, Inhibition of p75 Tumor Necrosis Factor Receptor by Antisense Oligonucleotides Increases Hypoxic Injury and β-Amyloid Toxicity in Human Neuronal Cell Line Journal of Biological Chemistry. ,vol. 272, pp. 3550- 3553 ,(1997) , 10.1074/JBC.272.6.3550
Christian P. Beltinger, Peter S. White, John M. Maris, Erik P. Sulman, Sanford J. Jensen, Denis LePaslier, Barbara J. Stallard, David V. Goeddel, Frederic J. de Sauvage, Garrett M. Brodeur, Physical mapping and genomic structure of the human TNFR2 gene Genomics. ,vol. 35, pp. 94- 100 ,(1996) , 10.1006/GENO.1996.0327
Marleen M.J. van Greevenbroek, Carla J.H. van der Kallen, Jan M.W. Geurts, Rob G.J.H. Janssen, Wim A. Buurman, Tjerk W.A. de Bruin, Soluble receptors for tumor necrosis factor-α (TNF-R p55 and TNF-R p75) in familial combined hyperlipidemia Atherosclerosis. ,vol. 153, pp. 1- 8 ,(2000) , 10.1016/S0021-9150(00)00375-0
Andrea D. Branch, A good antisense molecule is hard to find Trends in Biochemical Sciences. ,vol. 23, pp. 45- 50 ,(1998) , 10.1016/S0968-0004(97)01155-9
Annadora J. Bruce, Warren Boling, Mark S. Kindy, Jacques Peschon, Philipp J. Kraemer, Melissa K. Carpenter, Frederick W. Holtsberg, Mark P. Mattson, Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors Nature Medicine. ,vol. 2, pp. 788- 794 ,(1996) , 10.1038/NM0796-788