Biodesulfurization: a model system for microbial physiology research

作者: John J. Kilbane , Benjamin Stark

DOI: 10.1007/S11274-016-2084-6

关键词:

摘要: Biological desulfurization (biodesulfurization) of dibenzothiophene (DBT) by the 4S pathway is a model system for an enviromentally benign way to lower sulfur content petroleum. Despite large amount effort efficiency still too low commercial oil biodesulfurization process, but could potentially be used now processes produce surfactants, antibiotics, polythioesters and other chemicals detoxification some chemical warfare agents. Proteins containing disulfide bonds are resistant temperature, pH, solvents, production disulfide-rich proteins in microbial hosts challenging. The study can provide insights as how maximize proteins. Engineering operon encoding contain greater methionine cysteine may able link use DBT sole source increasing activity nutritional demand sulfur. This strategy result development biocatalysts suitable also lead better understanding physiology optimize mult-step co-factor-requiring pathway, well highly stable industrially relevant enzymes numerous applications.

参考文章(43)
Tak-Hang Chan, Chao-Jun Li, Comprehensive Organic Reactions in Aqueous Media ,(2007)
Bo Yu, Fei Tao, Fuli Li, Jianfeng Hou, Hongzhi Tang, Cuiqing Ma, Ping Xu, Complete genome sequence of Mycobacterium goodii X7B, a facultative thermophilic biodesulfurizing bacterium with industrial potential. Journal of Biotechnology. ,vol. 212, pp. 56- 57 ,(2015) , 10.1016/J.JBIOTEC.2015.08.004
Bin Jiang, Huawei Yang, Luhong Zhang, Rongya Zhang, Yongli Sun, Yong Huang, Efficient oxidative desulfurization of diesel fuel using amide-based ionic liquids Chemical Engineering Journal. ,vol. 283, pp. 89- 96 ,(2016) , 10.1016/J.CEJ.2015.07.070
Stathis Frillingos, Miklós Sahin‐Tóth, Jianhua Wu, H. Ronald Kaback, Cys-scanning mutagenesis: a novel approach to structure–function relationships in polytopic membrane proteins The FASEB Journal. ,vol. 12, pp. 1281- 1299 ,(1998) , 10.1096/FASEBJ.12.13.1281
Jinny L. Liu, Ellen R. Goldman, Dan Zabetakis, Scott A. Walper, Kendrick B. Turner, Lisa C. Shriver-Lake, George P. Anderson, Enhanced production of a single domain antibody with an engineered stabilizing extra disulfide bond Microbial Cell Factories. ,vol. 14, pp. 158- 158 ,(2015) , 10.1186/S12934-015-0340-3
K. J. Kayser, L. Cleveland, H.-S. Park, J.-H. Kwak, A. Kolhatkar, J. J. Kilbane, Isolation and characterization of a moderate thermophile, Mycobacterium phlei GTIS10, capable of dibenzothiophene desulfurization Applied Microbiology and Biotechnology. ,vol. 59, pp. 737- 745 ,(2002) , 10.1007/S00253-002-1030-8
Nadège Liaud, Marie-Noëlle Rosso, Nicolas Fabre, Sylvaine Crapart, Isabelle Herpoël-Gimbert, Jean-Claude Sigoillot, Sana Raouche, Anthony Levasseur, L-lactic acid production by Aspergillus brasiliensis overexpressing the heterologous ldha gene from Rhizopus oryzae. Microbial Cell Factories. ,vol. 14, pp. 66- 66 ,(2015) , 10.1186/S12934-015-0249-X
Jie Pan, Fan Wu, Jia Wang, Linqing Yu, Naghmeh Hassanzadeh Khayyat, Benjamin C. Stark, John J. Kilbane, Enhancement of desulfurization activity by enzymes of the Rhodococcus dsz operon through coexpression of a high sulfur peptide and directed evolution Fuel. ,vol. 112, pp. 385- 390 ,(2013) , 10.1016/J.FUEL.2013.04.065
V. G. Debabov, Microbial desulfurization of motor fuel Applied Biochemistry and Microbiology. ,vol. 46, pp. 733- 738 ,(2010) , 10.1134/S0003683810080016
Duncan Seddon, Reformulated gasoline, opportunities for new catalyst technology Catalysis Today. ,vol. 15, pp. 1- 21 ,(1992) , 10.1016/0920-5861(92)80120-C