Pycnanthuquinone C, an unusual 6,6,5-tricyclic Geranyltoluquinone from the Western Australian brown alga Cystophora harveyi.

摘要: Chemical investigation of the Western Australian marine brown alga Cystophora harveyi resulted in isolation new linearly fused 6,6,5-tricyclic compound pycnanthuquinone C (1), addition to four previously reported geranyltoluquinol derivatives. Structures were elucidated by interpretation spectrometric data. Compounds with same cyclic skeleton as 1 have been be useful drug leads for treatment type 2 diabetes, while compounds 4 and 7 are known constituents Chinese medicinal herbs. A biosynthetic scheme encompassing all derivatives isolated from C. is proposed.