作者: Glenn P. Cruse , Dean D. Metcalfe
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摘要: Methods for treating diseases and conditions mediated by the high affinity IgE receptor (FceRI). Antisense oligomers modulating splicing of mRNA encoding FceRIβ protein, thereby down-regulating cell-surface expression FceRI, uses antisense inhibiting mast cell degranulation, cytokine release, migration, proliferation.