作者: David Spetzler , Tassilo Hornung , Valeriy Domenyuk , Frank Schafer , David Halbert
DOI:
关键词: Microvesicle 、 Aptamer 、 Computational biology 、 Molecular biology 、 Biology
摘要: Methods and compositions are provided for specific aptamers aptamer pools that bind biomarkers of interest such as microvesicle surface antigens or functional fragments antigens. In various embodiments, the invention used in diagnostic, prognostic, theranostic processes to screen a biological sample presence levels micro vesicles determined provide readout. The diagnosis, prognosis, theranosis may be related cancer other diseases disorders. also provides methods composition facilitate library screening detection methods.