Method for screening nucleic acid ligand

摘要: Provided is a method for screening library of candidate nucleic acid ligand. The includes the steps of: (a) preparing ligands; (b) contacting, under absence target substance, with supporting member binding to at least one conserved sequence domains included in ligand, and then separating removing ligand which does not form an intermolecular duplex; (c) dissociating duplex by presence substance remaining forming obtained step (b), collecting having specific secondary structure formed wherein time (c).