Epcam aptamers and conjugates thereof

作者: Sarah Shigdar

DOI:

关键词:

摘要: The present disclosure relates to an EpCAM aptamer or conjugate having bi-functional activity and uses thereof. In particular, the also which binds transferrin receptor (TfR) is useful for treatment of brain tumours and/or metastasis.

参考文章(32)
David Spetzler, Tassilo Hornung, Valeriy Domenyuk, Frank Schafer, David Halbert, Nianqing Xiao, Aptamers and uses thereof ,(2013)
Wei Duan, Epcam aptamer for detection of cancer stem cells EpCAM Aptamer for Detection of Cancer Stem Cells. ,(2013)
Vaishali Bagalkot, Benjamin Teply, Omid C. Farokhzad, Etgar Levy-Nissenbaum, Liangfang Zhang, Robert S. Langer, Sangyong Jon, Aptamer-directed drug delivery ,(2007)
Samantha E. Wilner, Keith Everett Maier, Matthew Levy, Transferrin receptor aptamers and aptamer-targeted delivery ,(2013)
Michael J Gait, Oligonucleotide synthesis : a practical approach Published in <b>1984</b> in Oxford by IRL press. ,(1984)
Wei Duan, Cd133 aptamers for detection of cancer stem cells CD133 Aptamers for Detection of Cancer Stem Cells. ,(2013)
Vikas Khetan, Sailaja V. Elchuri, Jagat R. Kanwar, Rupinder K. Kanwar, Subramanian Krishnakumar, Nithya Subramanian, Vaishnavi Raghunathan, Target-specific delivery of doxorubicin to retinoblastoma using epithelial cell adhesion molecule aptamer Molecular Vision. ,vol. 18, pp. 2783- 2795 ,(2012)
Guizhi Zhu, Ling Meng, Mao Ye, Liu Yang, Kwame Sefah, Meghan B. O'Donoghue, Yan Chen, Xiangling Xiong, Jin Huang, Erqun Song, Weihong Tan, Self‐Assembled Aptamer‐Based Drug Carriers for Bispecific Cytotoxicity to Cancer Cells Chemistry – An Asian Journal. ,vol. 7, pp. 1630- 1636 ,(2012) , 10.1002/ASIA.201101060
Ashley Cimino, Marc Halushka, Peter Illei, Xinyan Wu, Saraswati Sukumar, Pedram Argani, Epithelial cell adhesion molecule (EpCAM) is overexpressed in breast cancer metastases Breast Cancer Research and Treatment. ,vol. 123, pp. 701- 708 ,(2010) , 10.1007/S10549-009-0671-Z