Genomic characterization of the non-O1/non-O139 Vibrio cholerae strain that caused a gastroenteritis outbreak in Santiago, Chile, 2018.
作者： Mónica Arteaga , Juliana Velasco , Shelly Rodriguez , Maricel Vidal , Carolina Arellano
关键词:
摘要: Vibrio cholerae is a human pathogen, which transmitted by the consumption of contaminated food or water. V. strains belonging to serogroups O1 and O139 can cause cholera outbreaks epidemics, severe life-threatening diarrheal disease. In contrast, other than O139, denominated as non-O1/non-O139, have been mainly associated with sporadic cases moderate mild diarrhea, bacteremia wound infections. Here we investigated virulence determinants phylogenetic origin non-O1/non-O139 strain that caused gastroenteritis outbreak in Santiago, Chile, 2018. We found this lacks classical genes harboured strains, including toxin (CT) toxin-coregulated pilus (TCP). However, carries genomic islands (GIs) encoding Type III VI secretion systems (T3SS/T6SS) antibiotic resistance genes. Moreover, these GIs are wide distributed among several lineages strains. Our results suggest acquisition may enhance lack CT TCP-encoding highlight pathogenic potential
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sci-hub.st 参考文章(36)
M. Pichel, A. Villagra de Trejo, M. I. Caffer, S. Figueroa, M. Cecilia de Castillo, N. Binsztein, S. González Fraga, G. Merletti, Caracterización de aislamientos de Vibrio cholerae no-O1, no-O139 asociados a cuadros de diarrea Revista Argentina De Microbiologia. ,vol. 41, pp. 11- 19 ,(2009)
Miguel O’Ryan, Roberto Vidal, Felipe del Canto, Juan Carlos Salazar, David Montero, None, Vaccines for viral and bacterial pathogens causing acute gastroenteritis: Part I: Overview, vaccines for enteric viruses and Vibrio cholerae. Human Vaccines & Immunotherapeutics. ,vol. 11, pp. 584- 600 ,(2015) , 10.1080/21645515.2015.1011019
S. Deshayes, C. Daurel, V. Cattoir, J.-J. Parienti, M.-L. Quilici, A. de La Blanchardière, Non-O1, non-O139 Vibrio cholerae bacteraemia: case report and literature review SpringerPlus. ,vol. 4, pp. 575- 575 ,(2015) , 10.1186/S40064-015-1346-3
Ramy K Aziz, Daniela Bartels, Aaron A Best, Matthew DeJongh, Terrence Disz, Robert A Edwards, Kevin Formsma, Svetlana Gerdes, Elizabeth M Glass, Michael Kubal, Folker Meyer, Gary J Olsen, Robert Olson, Andrei L Osterman, Ross A Overbeek, Leslie K McNeil, Daniel Paarmann, Tobias Paczian, Bruce Parrello, Gordon D Pusch, Claudia Reich, Rick Stevens, Olga Vassieva, Veronika Vonstein, Andreas Wilke, Olga Zagnitko, The RAST Server: Rapid Annotations using Subsystems Technology BMC Genomics. ,vol. 9, pp. 75- 75 ,(2008) , 10.1186/1471-2164-9-75
Teresa M. Brooks, Daniel Unterweger, Verena Bachmann, Benjamin Kostiuk, Stefan Pukatzki, Lytic Activity of the Vibrio cholerae Type VI Secretion Toxin VgrG-3 is Inhibited by the Antitoxin TsaB Journal of Biological Chemistry. ,vol. 288, pp. 7618- 7625 ,(2013) , 10.1074/JBC.M112.436725
Rolf S Kaas, Pimlapas Leekitcharoenphon, Frank M Aarestrup, Ole Lund, None, Solving the Problem of Comparing Whole Bacterial Genomes across Different Sequencing Platforms PLoS ONE. ,vol. 9, pp. e104984- ,(2014) , 10.1371/JOURNAL.PONE.0104984
Christopher A. Broberg, Thomas J. Calder, Kim Orth, Vibrio parahaemolyticus cell biology and pathogenicity determinants. Microbes and Infection. ,vol. 13, pp. 992- 1001 ,(2011) , 10.1016/J.MICINF.2011.06.013
Devarati Dutta, Goutam Chowdhury, Gururaja P Pazhani, Sucharita Guin, Sanjucta Dutta, Santanu Ghosh, K Rajendran, Ranjan K Nandy, Asish K Mukhopadhyay, Mihir K Bhattacharya, Utpala Mitra, Yoshifumi Takeda, G Balakrish Nair, Thandavarayan Ramamurthy, None, Vibrio cholerae Non-O1, Non-O139 Serogroups and Cholera-like Diarrhea, Kolkata, India Emerging Infectious Diseases. ,vol. 19, pp. 464- 467 ,(2013) , 10.3201/EID1903.121156
Jun Zheng, Brian Ho, John J. Mekalanos, Genetic Analysis of Anti-Amoebae and Anti-Bacterial Activities of the Type VI Secretion System in Vibrio cholerae PLoS ONE. ,vol. 6, pp. e23876- ,(2011) , 10.1371/JOURNAL.PONE.0023876
Yanyan Zhou, Li Yu, Jie Li, Lijuan Zhang, Ying Tong, Biao Kan, Accumulation of mutations in DNA gyrase and topoisomerase IV genes contributes to fluoroquinolone resistance in Vibrio cholerae O139 strains. International Journal of Antimicrobial Agents. ,vol. 42, pp. 72- 75 ,(2013) , 10.1016/J.IJANTIMICAG.2013.03.004