Gender and Ethnic Disparities in Incidence and Survival of Squamous Cell Carcinoma of the Oral Tongue, Base of Tongue, and Tonsils: A Surveillance, Epidemiology and End Results Program-Based Analysis

摘要: Background: Squamous cell carcinomas (SCC) of the oral tongue (OT) and base tonsils (BTT) differ with respect to etiology, treatment prognosis. Human papillomavirus has been linked increased incidence BTT, yet, trends in BTT OT tumors among gender ethnic origin groups have not well examined. We sought examine trend gender-, origin- age-specific these over time. Methods: Data were obtained from Surveillance, Epidemiology End Results Program US National Cancer Institute. examined temporal sex- origin-specific SCC by calculating annual percent changes followed joinpoint analyses evaluating trend. Results: While age-adjusted rates white males a more pronounced increase observed mid-1990s, females experienced significant tumors. Patients advanced carcinoma had significantly lower survival compared those disease; however, patients early-stage better BTT. Conclusions: men is likely human driven, studies are needed elucidate increasing women. The differences outcomes across also described discussed.