作者: E. B. Papas , C.M. Vajdic , R. Austen , B.A. Holden
DOI: 10.1076/CEYR.16.9.942.5049
关键词:
摘要: PURPOSE. To establish the temporal sequence of limbal hyperaemia in humans without contact-lens wear and during conventional highly oxygen-permeable soft-contact-lens wear. METHODS. Two, 16-h, non-dispensing clinical studies were conducted, each incorporating 8 h open eye with normal blinking, followed by closure sleep. In first study, six non-habitual wearers did not contact lenses. second same subjects randomly assigned, a double-masked fashion, to conventional, thin, 38% water, pHEMA soft lense (SCL) one an experimental high Dk (EHD), 20%-water lens other. Limbal redness (LR) was graded, using 0–4 scale decimalised subdivisions, at baseline after 4, 16 h. ANOVA applied data, level for statistical significance set p = 0.005. RESULTS. non-wearing eye, LR changes averaged 0.2 ± 0.4 grades 4 h, respectively (inf...