Sildenafil citrate therapy for pulmonary arterial hypertension.
作者： Nazzareno Galiè , Hossein A. Ghofrani , Adam Torbicki , Robyn J. Barst , Lewis J. Rubin
DOI: 10.1056/NEJMOA050010
关键词:
摘要: … , 20 mg of sildenafil, and 40 mg of sildenafil received 40 mg of sildenafil for the first six weeks of the extension study, and the dose was then increased to 80 mg of sildenafil. Patients …
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pneumonologia.gr 参考文章(39)
Evangelos Michelakis, Wayne Tymchak, Dale Lien, Linda Webster, Kyoko Hashimoto, Stephen Archer, Oral Sildenafil Is an Effective and Specific Pulmonary Vasodilator in Patients With Pulmonary Arterial Hypertension Comparison With Inhaled Nitric Oxide Circulation. ,vol. 105, pp. 2398- 2403 ,(2002) , 10.1161/01.CIR.0000016641.12984.DC
Marc Humbert, Nicholas W Morrell, Stephen L Archer, Kurt R Stenmark, Margaret R MacLean, Irene M Lang, Brian W Christman, E Kenneth Weir, Oliver Eickelberg, Norbert F Voelkel, Marlene Rabinovitch, None, Cellular and molecular pathobiology of pulmonary arterial hypertension. Journal of the American College of Cardiology. ,vol. 43, ,(2004) , 10.1016/J.JACC.2004.02.029
Nikki L. Jernigan, Thomas C. Resta, Chronic hypoxia attenuates cGMP-dependent pulmonary vasodilation. American Journal of Physiology-lung Cellular and Molecular Physiology. ,vol. 282, ,(2002) , 10.1152/AJPLUNG.00273.2001
J PEPKE-ZABA, TW HIGENBOTTAM, AT DINH-XUAN, D STONE, J WALLWORK, None, Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension. The Lancet. ,vol. 338, pp. 1173- 1174 ,(1991) , 10.1016/0140-6736(91)92033-X
Jackie D. Corbin, Sharron H. Francis, Cyclic GMP phosphodiesterase-5: target of sildenafil. Journal of Biological Chemistry. ,vol. 274, pp. 13729- 13732 ,(1999) , 10.1074/JBC.274.20.13729
Lewis J. Rubin, David B. Badesch, Robyn J. Barst, Nazzareno Galiè, Carol M. Black, Anne Keogh, Tomas Pulido, Adaani Frost, Sébastien Roux, Isabelle Leconte, Michael Landzberg, Gérald Simonneau, Bosentan therapy for pulmonary arterial hypertension. The New England Journal of Medicine. ,vol. 346, pp. 896- 903 ,(2002) , 10.1056/NEJMOA012212
Hossein A Ghofrani, Joanna Pepke-Zaba, Joan A Barbera, Richard Channick, Anne M Keogh, Miguel A Gomez-Sanchez, Meinhard Kneussl, Friedrich Grimminger, Nitric oxide pathway and phosphodiesterase inhibitors in pulmonary arterial hypertension. Journal of the American College of Cardiology. ,vol. 43, ,(2004) , 10.1016/J.JACC.2004.02.031
B. Tantini, A. Manes, E. Fiumana, C. Pignatti, C. Guarnieri, R Zannoli, A. Branzi MD, N. Gali�, Antiproliferative effect of sildenafil on human pulmonary artery smooth muscle cells Basic Research in Cardiology. ,vol. 100, pp. 131- 138 ,(2005) , 10.1007/S00395-004-0504-5
Richard N. Channick, John W. Newhart, F. Wayne Johnson, Penny J. Williams, William R. Auger, Peter F. Fedullo, Kenneth M. Moser, Pulsed Delivery of Inhaled Nitric Oxide to Patients With Primary Pulmonary Hypertension: An Ambulatory Delivery System and Initial Clinical Tests Chest. ,vol. 109, pp. 1545- 1549 ,(1996) , 10.1378/CHEST.109.6.1545
Horst Olschewski, Gerald Simonneau, Nazzareno Galiè, Timothy Higenbottam, Robert Naeije, Lewis J. Rubin, Sylvia Nikkho, Rudolf Speich, Marius M. Hoeper, Jürgen Behr, Jörg Winkler, Olivier Sitbon, Wladimir Popov, H. Ardeschir Ghofrani, Alessandra Manes, David G. Kiely, Ralph Ewert, Andreas Meyer, Paul A. Corris, Marion Delcroix, Miguel Gomez-Sanchez, Harald Siedentop, Werner Seeger, Inhaled iloprost for severe pulmonary hypertension. The New England Journal of Medicine. ,vol. 347, pp. 322- 329 ,(2002) , 10.1056/NEJMOA020204