Effect of corn oil feeding on lipid peroxidation in rats.

摘要: Three groups of male rats were maintained on 10% fat diets containing 0.5, 5 or corn oil olive with 80--400 mg DL-alpha-tocopherol per kilogram. After 4 weeks such regimens, TBA (thiobarbituric acid) values in serum, liver mitochondria and microsomes, adipose tissue increased rising amounts dietary oil. fed the diet reduced increase tocopherol but still higher than corresponding 0.5% groups. When microsomes incubated Fe3+-ADP NADPH, relative chemiluminescence emission visible region peroxidative cleavage endogenous lipid was group. On other hand, when oxidized given orally to thoracic lymph fistula, TBA-reacting substances recovered lymph, iodometric peroxide undetectable. Therefore, could have originated from oxidative product linoleic acid metabolism also diet.