Mass spectrometric identification of various molecular forms of dynorphin in bovine adrenal medulla.
作者： Simon Lemaire , Lucie Chouinard , Danielle Denis , Maria Panico , Howard R. Morris
DOI: 10.1016/0006-291X(82)91830-7
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摘要: Abstract Two dynorphin-(Dyn) immunoreactive fractions (I and II) were isolated from bovine adrenal medulla. On Fast Atom Bombardment (FAB) mass spectrometry, fraction I was identified as Dyn-(1–12) II shown to be a mixture of Dyn-(1–11), Dyn-(1–13) two modified forms with molecular weights exceeding that the parent peptide by 14 28, respectively. These results suggest Dyn-biosynthetic pathway may generate different types biologically active molecules.
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