Fibulins: physiological and disease perspectives

作者: W Scott Argraves , Lisa M Greene , Marion A Cooley , William M Gallagher

DOI: 10.1038/SJ.EMBOR.7400033

关键词:

摘要: The fibulins are a family of proteins that associated with basement membranes and elastic extracellular matrix fibres. This review summarizes findings from studies animal models fibulin deficiency, human gene mutations, tumours injury have advanced our understanding the normal pathological roles members this formerly obscure family.

参考文章(62)
Jing Qing, Veronica M Maher, Huan Tran, W Scott Argraves, Robert W Dunstan, J Justin McCormick, Suppression of anchorage-independent growth and matrigel invasion and delayed tumor formation by elevated expression of fibulin-1D in human fibrosarcoma-derived cell lines Oncogene. ,vol. 15, pp. 2159- 2168 ,(1997) , 10.1038/SJ.ONC.1201385
Sridhar Ramaswamy, Ken N. Ross, Eric S. Lander, Todd R. Golub, A molecular signature of metastasis in primary solid tumors. Nature Genetics. ,vol. 33, pp. 49- 54 ,(2003) , 10.1038/NG1060
Yasutaka Hayashido, Annick Lucas, Christian Rougeot, Svetlana Godyna, W. Scott Argraves, Henri Rochefort, Estradiol and fibulin-1 inhibit motility of human ovarian- and breast-cancer cells induced by fibronectin. International Journal of Cancer. ,vol. 75, pp. 654- 658 ,(1998) , 10.1002/(SICI)1097-0215(19980209)75:4<654::AID-IJC26>3.0.CO;2-7
Günter Kostka, Richard Giltay, Wilhelm Bloch, Klaus Addicks, Rupert Timpl, Reinhard Fässler, Mon-Li Chu, Perinatal Lethality and Endothelial Cell Abnormalities in Several Vessel Compartments of Fibulin-1-Deficient Mice Molecular and Cellular Biology. ,vol. 21, pp. 7025- 7034 ,(2001) , 10.1128/MCB.21.20.7025-7034.2001
Shazia S Chaudhry, James Gazzard, Clair Baldock, Jill Dixon, Matthew J Rock, Gail C Skinner, Karen P Steel, Cay M Kielty, Michael J Dixon, Mutation of the gene encoding fibrillin-2 results in syndactyly in mice Human Molecular Genetics. ,vol. 10, pp. 835- 843 ,(2001) , 10.1093/HMG/10.8.835
Ping-Ping Kuang, Ronald H. Goldstein, Yue Liu, David C. Rishikof, Jyh-Chang Jean, Martin Joyce-Brady, Coordinate expression of fibulin-5/DANCE and elastin during lung injury repair American Journal of Physiology-lung Cellular and Molecular Physiology. ,vol. 285, ,(2003) , 10.1152/AJPLUNG.00098.2003
G. M. Clinton, C. Rougeot, J. Derancourt, P. Roger, A. Defrenne, S. Godyna, W. S. Argraves, H. Rochefort, Estrogens increase the expression of fibulin-1, an extracellular matrix protein secreted by human ovarian cancer cells. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 93, pp. 316- 320 ,(1996) , 10.1073/PNAS.93.1.316
Kayla J. Bayless, George E. Davis, Steven A. Maxwell, Anil Mavila, Scott E. Bell, Suhasini Kanagala, René Salazar, Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling. Journal of Cell Science. ,vol. 114, pp. 2755- 2773 ,(2001) , 10.1242/JCS.114.15.2755
W S Argraves, H Tran, W H Burgess, K Dickerson, Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure. Journal of Cell Biology. ,vol. 111, pp. 3155- 3164 ,(1990) , 10.1083/JCB.111.6.3155